Clinical Info

NEPHROSPEC

It Comes As a Shock
Kidney Repair Using Shockwave Therapy

Nattawat Klomjit, Amir Lerman, Lilach O. Lerman

DOI: 10.1161/HYPERTENSIONAHA.120.14595, 2019

Abstract: Chronic kidney disease is a global health care burden, yet clinically-proven treatments are limited. Low-intensity shockwave, which utilizes ≈10% of the energy levels used in clinically indicated shockwave lithotripsy, is a promising technique to ameliorate ischemia and regenerate tissues…

Low–Energy Shockwave Therapy Improves Ischemic
Kidney Microcirculation

Xin Zhang, James D. Krier, Carolina Amador Carrascal, James F. Greenleaf, Behzad Ebrahimi, Ahmad F. Hedayat, Stephen C. Textor, Amir Lerman and Lilach O. Lerman

J Am Soc Nephrol 27: 3715–3724, 2016. doi: 10.1681/ASN.2015060704

Abstract: Microvascular rarefaction distal to renal artery stenosis is linked to renal dysfunction and poor outcomes. Low–energy shockwave therapy stimulates angiogenesis, but the effect on the kidney microvasculature is unknown. We hypothesized that low–energy shockwave therapy would restore the…

Magnetic Resonance Elastography Can
Monitor Changes in Medullary Stiffness in
Response to Treatment in the Swine Ischemic
Kidney

Xin Zhang, Xiangyang Zhu, Christopher Martyn Ferguson, Kai Jiang, Tyson Burningham, Amir Lerman & Lilach Orly Lerman

Magn Reson Mater Phy DOI 10.1007/s10334-017-0671-7, 2017

Abstract: Objective: Low-energy shockwave (SW) therapy attenuates damage in the stenotic kidney (STK) caused by atherosclerotic renal artery stenosis (ARAS). We hypothesized that magnetic resonance elastography (MRE) would detect attenuation of fibrosis following SW in unilateral ARAS kidneys…